Update History
  • Our mGWAS 2.0 paper is now published on Metabolites! (07/03/2023);
  • Fixed a bug with the seed number count for complex queries (06/22/2023);
  • New tutorials now available! Explore MR Analysis and the Browse mPheWAS module with our latest guides.(06/07/2023);
  • Added R command history panel (05/30/2023);
  • Minor code cleaning and fixed home page navigation (05/27/2023);
  • Switched to using local plink files for LD proxy search (05/05/2023);
  • Switched to MyVariant for SNP annotation (03/21/2023);
  • Added Miami plot to visualize significant results of mPheWAS in both phenome-wide and metabolome-wide view (03/17/2023);
  • Added support for auto-complete when searching exposures/outcomes (03/16/2023);
  • Added a new module to support browsing the results of phenome-wide MR of metabolome (03/14/2023);
  • Switched to local LD clumping to decrease processing time, compared to using the external API (01/26/2023);
  • Added PMID links in literature evidence (01/17/2023);
  • Added support to search literature evidence (i.e., semantic triples) in MR module (01/14/2023);
  • Fixed bugs in MR analysis module (01/08/2023);
  • Added support to perform pQTL (protein quantitative trait loci) mapping (01/03/2023);
  • Fixed bugs in network view (12/30/2022);
  • Added a tutorial for two-sample Mendelian randomization analysis module (12/06/2022);
  • Added support to customize the graphics output (11/14/2022);
  • Added support for two-sample Mendelian randomization (11/04/2022);
  • Improved homepage design (10/19/2022);
  • Use the "Resources" top menu item to access the mGWAS studies (previous "Browse" module) (10/15/2022);
  • Added Download page to support downloading result tables and images; (10/11/2022);
  • Added Rasa chatbot; (10/09/2022);
  • Upgraded to Prime Faces 12.0.0; (10/08/2022);
  • Code cleaning and refactoring for better performance (09/26/2022);
  • Added support for auto-complete in search box (09/19/2022);
  • Added support to search both SNPs and/or metabolties (08/30/2022);
  • Updated search module (08/12/2022);
  • Fixed bugs and updated SNP-gene-metabolite network in the SNP module (07/15/2022);
  • Please join our OmicsForum to ask questions or share experiences related to mGWAS-Explorer (06/15/2022);
  • Code cleaning and refactoring for better performance (05/31/2022);
  • Added support for metabolite-disease and gene-disease network (05/23/2022);
  • Redesigned home page (05/20/2022);
  • Updated tutorials and FAQs (05/13/2022);
  • Fixed issues with table browsing and table statistics (05/10/2022);
  • Fixed issues with highlighting seed nodes function (05/10/2022);
  • Improved name mapping functions for common metabolite names (05/09/2022);
  • Added support to integrate with PPI network (04/18/2022);
  • Added support for LD proxy search (04/16/2022);
  • Added three options for variant annotation, including HaploReg, PhenoScanner, and VEP (04/14/2022);
  • Added four gene set libraries for enrichment analysis based on DisGeNET, Orphanet, DrugMatrix, and DSigDB (03/29/2022);
  • Added 3D Manhattan plot visualization (01/28/2022);
  • Users can now explore SNP-metabolite association network of individual mGWA study from the "Resources" page (01/21/2022);
  • Check out our video tutorials for intuitive network visual analytics (01/07/2022);
  • Updated "Network Tools" for better network refinement (01/04/2022);
  • Updated FAQs, Tutorials, and Resource pages (01/01/2022);
  • Added the "Module Explorer" panel for better network visual analytics (12/28/2021);
  • Updated variant set enrichment analysis (12/22/2021);
  • Upgraded to PrimeFaces v11 (12/20/2021);
  • Added common network topology measures in the Network Builder page (12/19/2021);
  • Code cleaning and refactoring (12/18/2021);
  • Added support to browse table results (12/16/2021);
  • Added support for disease-SNP-metabolite composite network (12/15/2021);
  • Updated documentation (12/13/2021);
  • Added support to download network in JSON, PNG, SVG, and table format (12/12/2021);
  • Added support to search nodes in the network (12/08/2021);
  • Updated the network viewer page in the Explore module (12/08/2021);
  • Merged explore network modules into one module (12/02/2021);
  • Added a module to explore SNP network in a hierarchical view (12/02/2021);
  • Added a module to explore drug network in a hierarchical view (11/25/2021);
  • Added a module to explore metabolite network in a hierarchical view (11/23/2021);
  • Updated disease to SNP and metabolite to SNP network (11/19/2021);
  • Added hierarchical network viewing (3 levels) (11/16/2021);
  • Added support to perform eQTL mapping (11/11/2021);
  • Added a module to explore disease network (11/10/2021);
  • Updated FAQs (11/04/2021);
  • Updated table view page (11/04/2021);
  • Added SNP browse module (11/03/2021);
  • Updated homepage (10/28/2021);
  • Added support for metabolite-disease network searching and exploring (10/27/2021);
  • Added network option dialog in metabolite upload page (10/26/2021);
  • Added support to update disease names based on disease classes (10/25/2021);
  • Added support for SNP-disease mapping (10/22/2021);
  • Optimized workflow => directly proceed to network builder page after data upload (10/21/2021);
  • Added a module to support uploading metabolites (10/19/2021);
  • Code cleaning + updated network functions and viewer page (10/18/2021);
  • Added master compound libraries (10/04/2021);
  • Updated KEGG global metabolic map libraries (09/11/2021);
  • Updated browse view, including upload and table view page (09/11/2021);
  • Fixed issues with loading subnetworks (09/03/2021);
  • Updated study_metabolite table and added study meta data (09/02/2021);
  • Added support for network analysis for SNP-metabolite associations (09/02/2021);
  • Fixed issues with transparent background in SelectOneMenu (09/02/2021);
  • Updated advanced filters in table view (09/01/2021);
  • Updated tutorials and FAQs (08/31/2021);
  • Added track index for ideogram according to impact of the SNPs (08/26/2021);
  • Updated example dataset for SNP and gene module (08/25/2021);
  • Added support to search by PubChem, ChEBI, and METLIN ID (08/25/2021);
  • Added support for GSEA and MSEA (08/17/2021);
  • Added ideogram visualization at the table view page (08/08/2021);
  • Updated interface for database query (08/06/2021);
  • Added p-value column to results table (08/04/2021);
  • Added example data for knowledge-driven network integration (12/14/2020);
  • Added approximate matching for compound name (12/12/2020);
  • Fixed bugs in ideogram chromosome view (12/01/2020);
  • Standardized metabolites' common name (11/30/2020);
  • Updated KEGG global metabolic map (11/25/2020);
  • Updated ideogram.js from 1.5.0 to 1.28.0 (11/20/2020);
  • Added support for gene enrichment analysis on Network view (04/06/2019);
  • Updated homepage and FAQs (04/06/2019);
  • Added the biofluid types of the collected SNP-Metabolite associations data (04/06/2019);
  • Resources page updates based on database statistics (03/24/2019);
  • Added Network View for mapping metabolites to the KEGG metabolic pathway map (03/20/2019);
  • Added KEGG IDs for metabolites (03/16/2019);
  • Added chromosome ideogram for data visualization (03/15/2019);
  • Added annotations for SNPs from dbSNP (03/16/2019);
  • Collected 1093 SNP-metabolite association data from 38 mGWAS journals (03/30/2019);
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